Rapid development of ultra-sensitive biosensors enables rapid detection of trace contaminants in liquids

According to a recent report by the Physicist Organization Network, a research team at the University of New South Wales in Australia has developed a new biosensor that can detect trace amounts of contaminants in liquids in as little as 40 minutes. The research results were published in the latest edition of the German Journal of Applied Chemistry.

This sensor meets long-term challenges and is not only extremely sensitive, but also able to respond quickly. It has a wide range of potential applications for the detection of drugs, toxins and pesticides in the field of biomedicine or environmental analysis.

In the test experiment, the new sensor detected tiny traces of the veterinary antibiotic, enrofloxacin, present in milk. Justin, Professor of Physics, Chemical Nano Center, University of New South Wales. Goudin pointed out: "Enrofloxacin is an antibiotic used in agricultural production and can be transferred to the food chain. The new instrument can detect enrofloxacin up to nanogram level in one liter of milk in 40 minutes." The nanogram (nilligram) is one billionth of a gram and is the quality of a single cell.

The new biosensor can be used as a portable analysis device. The principle is to use gold-coated magnetic nanoparticles that are modified with selective chemical components. When this nanoparticle dissipates into the sample, encountering the analyte can cause some of the antibody to detach from the nanoparticle. Then, using a magnet, the nanoparticles can be assembled into a thin film that is measured between the two electrodes and the resistor. The more analytes are present, the more antibodies are isolated from the nanoparticles and the weaker the resistance of the nanoparticle films.

Justin. Gooding said: "The new type of biosensor can respond quickly to analytes, and it is also more sensitive than general biosensors, because the nanoparticles are dispersed throughout the sample and can analyze the entire sample, not just a small part of it. "(Hua Ling)

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